The Morris–Lecar neuron model embeds a leaky integrate-and-fire model

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The Morris-Lecar neuron model embeds a leaky integrate-and-fire model.

We show that the stochastic Morris-Lecar neuron, in a neighborhood of its stable point, can be approximated by a two-dimensional Ornstein-Uhlenbeck (OU) modulation of a constant circular motion. The associated radial OU process is an example of a leaky integrate-and-fire (LIF) model prior to firing. A new model constructed from a radial OU process together with a simple firing mechanism based o...

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ژورنال

عنوان ژورنال: Journal of Mathematical Biology

سال: 2012

ISSN: 0303-6812,1432-1416

DOI: 10.1007/s00285-012-0552-7